Endocrine Abstracts

Introduction: Endocrine late effects can manifest in hemopoietic stem cell transplantation survivors who were exposed to myelosuppressive conditioning treatment. These include dysfunction of the hypothalamic/pituitary, thyroid, and gonads leading to premature ovarian insufficiency and primary amenorrhoea. In addition, metabolic dysregulation and increased risk of diabetes have been observed in these patients. The investigation for primary amenorrhoea in this condition can rare...

Cyclic Cushing’s syndrome (CCS) is a rare condition that involves recurring episodes of hypercortisolaemia, alternating with normocortisolemia at intervals ranging from a few days to several years. To diagnose CCS, it is necessary to demonstrate three cortisol peaks and two troughs. CCS is mostly seen in females and can be Adrenocorticotropic hormone (ACTH)-dependent or independent2. The common causes of CCS are Cushing’s Disease (55% ), ectopic ACTH syndrome (26%), ...